The Winners is a band that is definitely past its peak. Looking for any way to spice up their act, the band is beginning to get desperate. Everything changes when bassist Jennifer (Jessica Pare) meets a vampire, and comes back from that encounter with a vampire bite and a matching taste for blood. The band suddenly finds immense popularity, thanks to their now sexy and irresistible bassist. As the band tours the country, their fame and popularity grows, and they leave behind a bloody trail. At the same time, vampire hunter Eddie Van Helsing (Malcolm McDowell) is hot on their trail, hoping to stop them before they can strike again.